Using probabilistic theory to develop interpretation guidelines for Y-STR profiles
نویسندگان
چکیده
منابع مشابه
Probabilistic characterisation of baseline noise in STR profiles.
There are three dominant contributing factors that distort short tandem repeat profile measurements, two of which, stutter and variations in the allelic peak heights, have been described extensively. Here we characterise the remaining component, baseline noise. A probabilistic characterisation of the non-allelic noise peaks is not only inherently useful for statistical inference but is also sig...
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Y-chromosome short tandem repeat (Y-STR) markers are being used as potential tools for distinguishing low levels of male DNA in the presence of excess female DNA as is present in many sexual assault samples. Usually single copy Y-STR loci produce a single amplicon in single source samples, and thus the observation of multiple peaks at such a locus could suggest to an analyst that a mixture of m...
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Y chromosome STR loci are used in forensics primarily for identification purposes by determining the male lineages. The Henan province in China has established a large Y-STR (>200 000 profiles) database for criminal investigations. A large proportion of the Y-STR profiles in the database were generated using either the Applied Biosystems Yfiler(ۛ) or Yfiler(ۛ) Plus PCR Amplification kits. The add...
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ژورنال
عنوان ژورنال: Forensic Science International: Genetics
سال: 2016
ISSN: 1872-4973
DOI: 10.1016/j.fsigen.2015.11.010